PauseOnError in Tulum
The next big airport is in Cancun. With direct flights from USA, Canada, Germany, Spain, Belgium, Argentina and many more, this should be easy reachable for most attendees. The hotel shuttle can pick you up from the airport.
I visited PauseOnError conference before in Berlin and Cleveland. Mexico as location has a big advantage and that is immigration. Not everyone can get the Visas for USA or Europe, so it may be easier to get to Tulum for some attendees. And for South American visitors, I expect this to be a cheaper alternative than FileMaker DevCon in Orlando.