As the new release changes graphics on Windows to use DirectDraw instead of GDI/GDI+, the plugins need to adapt. The handling on graphics ports (HDC) and for bitmap access changes a bit.
We recommend to use MBS Plugins in version 16.5 or newer with Xojo 2016r4. You can download pr9 now or wait for the release next week.
Download Xojo and see Release Notes. Review by Bob Keeney